BRD-K08316444_-666_PC3_24.0_h_0.63_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K08316444_-666_PC3_24.0_h_0.63_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CRISP3 cysteine-rich secretory protein 3
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSNK1E casein kinase 1, epsilon
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DDIT4 DNA-damage-inducible transcript 4
EDN1 endothelin 1
FCGBP Fc fragment of IgG binding protein
HIST1H2AE histone cluster 1, H2ae
HIST2H2BE histone cluster 2, H2be
IL1B interleukin 1, beta
IL7R interleukin 7 receptor
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
KIF20A kinesin family member 20A
KRT5 keratin 5, type II
LCN2 lipocalin 2
LOX lysyl oxidase
LPL lipoprotein lipase
MMP19 matrix metallopeptidase 19
PDZK1IP1 PDZK1 interacting protein 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100P S100 calcium binding protein P
SIK1 salt-inducible kinase 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLPI secretory leukocyte peptidase inhibitor
SRGN serglycin
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
C1S complement component 1, s subcomponent
CDCA4 cell division cycle associated 4
COG2 component of oligomeric golgi complex 2
COL6A3 collagen, type VI, alpha 3
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FXYD6 FXYD domain containing ion transport regulator 6
GINS2 GINS complex subunit 2 (Psf2 homolog)
KIAA0101 KIAA0101
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LUM lumican
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM6 minichromosome maintenance complex component 6
PALLD palladin, cytoskeletal associated protein
PLS1 plastin 1
RFC5 replication factor C (activator 1) 5, 36.5kDa
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SMAD1 SMAD family member 1
SULF1 sulfatase 1