BRD-K08109215_I-BET_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

121 genes differentially expressed following the BRD-K08109215_I-BET_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACBD3 acyl-CoA binding domain containing 3
ADCY9 adenylate cyclase 9
AGR2 anterior gradient 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BASP1 brain abundant, membrane attached signal protein 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BLNK B-cell linker
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPG capping protein (actin filament), gelsolin-like
CCDC92 coiled-coil domain containing 92
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CIRBP cold inducible RNA binding protein
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
CTGF connective tissue growth factor
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EZR ezrin
FAM127A family with sequence similarity 127, member A
FUCA1 fucosidase, alpha-L- 1, tissue
GRN granulin
GSN gelsolin
GSTP1 glutathione S-transferase pi 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA1A heat shock 70kDa protein 1A
IFI6 interferon, alpha-inducible protein 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JAG1 jagged 1
KDM5D lysine (K)-specific demethylase 5D
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PALLD palladin, cytoskeletal associated protein
PLAU plasminogen activator, urokinase
PNKP polynucleotide kinase 3'-phosphatase
PTGDS prostaglandin D2 synthase 21kDa (brain)
QPCT glutaminyl-peptide cyclotransferase
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RPL39L ribosomal protein L39-like
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RUNX3 runt-related transcription factor 3
SCPEP1 serine carboxypeptidase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SNX11 sorting nexin 11
SNX2 sorting nexin 2
SQSTM1 sequestosome 1
STXBP1 syntaxin binding protein 1
TRIM22 tripartite motif containing 22

decreased expression

Symbol Name
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AREG amphiregulin
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C2CD5 C2 calcium-dependent domain containing 5
C3 complement component 3
CCDC86 coiled-coil domain containing 86
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
COASY CoA synthase
CRYZ crystallin, zeta (quinone reductase)
DKC1 dyskeratosis congenita 1, dyskerin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPH2 DPH2 homolog (S. cerevisiae)
DUSP2 dual specificity phosphatase 2
EPN2 epsin 2
EREG epiregulin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FPGS folylpolyglutamate synthase
GAS2 growth arrest-specific 2
GRWD1 glutamate-rich WD repeat containing 1
GTF3A general transcription factor IIIA
IARS isoleucyl-tRNA synthetase
IFRD2 interferon-related developmental regulator 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IPO5 importin 5
LPAR6 lysophosphatidic acid receptor 6
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYPD1 LY6/PLAUR domain containing 1
MAPK13 mitogen-activated protein kinase 13
MEIS1 Meis homeobox 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDP Norrie disease (pseudoglioma)
NEFM neurofilament, medium polypeptide
NELL2 NEL-like 2 (chicken)
NOP56 NOP56 ribonucleoprotein
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDLIM1 PDZ and LIM domain 1
PIP prolactin-induced protein
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PXMP2 peroxisomal membrane protein 2, 22kDa
PYCR1 pyrroline-5-carboxylate reductase 1
RPIA ribose 5-phosphate isomerase A
S100P S100 calcium binding protein P
SCG5 secretogranin V
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLMO2 slowmo homolog 2 (Drosophila)
SNAP25 synaptosomal-associated protein, 25kDa
SORD sorbitol dehydrogenase
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SRM spermidine synthase
SRP72 signal recognition particle 72kDa
STEAP1 six transmembrane epithelial antigen of the prostate 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIM14 tripartite motif containing 14
XIST X inactive specific transcript (non-protein coding)
ZIC1 Zic family member 1
ZW10 zw10 kinetochore protein