BRD-K07859598_Raf1 Kinase Inhibitor I_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K07859598_Raf1 Kinase Inhibitor I_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5AP arachidonate 5-lipoxygenase-activating protein
CCL2 chemokine (C-C motif) ligand 2
CD200 CD200 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
DMD dystrophin
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ELMO1 engulfment and cell motility 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FSD1 fibronectin type III and SPRY domain containing 1
IDO1 indoleamine 2,3-dioxygenase 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
PDZK1IP1 PDZK1 interacting protein 1
PVALB parvalbumin
RAB21 RAB21, member RAS oncogene family
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFTPB surfactant protein B
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
STC1 stanniocalcin 1
STC2 stanniocalcin 2
SYNGR3 synaptogyrin 3
TCF4 transcription factor 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AGR2 anterior gradient 2
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AUTS2 autism susceptibility candidate 2
CAST calpastatin
CBR3 carbonyl reductase 3
CDCA4 cell division cycle associated 4
CPNE1 copine I
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DLC1 DLC1 Rho GTPase activating protein
ECM1 extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP2 epithelial membrane protein 2
ISLR immunoglobulin superfamily containing leucine-rich repeat
LUM lumican
NEBL nebulette
NR2F1 nuclear receptor subfamily 2, group F, member 1
PLAT plasminogen activator, tissue
POSTN periostin, osteoblast specific factor
PROM1 prominin 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBMS1 RNA binding motif, single stranded interacting protein 1
RBP1 retinol binding protein 1, cellular
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAND1 SCAN domain containing 1
SDC1 syndecan 1
SFN stratifin
STOM stomatin
TAGLN transgelin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TIMP3 TIMP metallopeptidase inhibitor 3
TPM1 tropomyosin 1 (alpha)
TSPAN4 tetraspanin 4
TSPYL5 TSPY-like 5
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1