BRD-K07237224_4-chloro-n-(2-morpholin-4-yl-ethyl)-benzamide_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K07237224_4-chloro-n-(2-morpholin-4-yl-ethyl)-benzamide_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
CD38 CD38 molecule
CTGF connective tissue growth factor
CTSB cathepsin B
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DLX2 distal-less homeobox 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ERBB4 erb-b2 receptor tyrosine kinase 4
FERMT2 fermitin family member 2
FKBP5 FK506 binding protein 5
FOXO3 forkhead box O3
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GJA1 gap junction protein, alpha 1, 43kDa
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GRB10 growth factor receptor-bound protein 10
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IGF1R insulin-like growth factor 1 receptor
INPP1 inositol polyphosphate-1-phosphatase
LGMN legumain
METTL7A methyltransferase like 7A
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSDHL NAD(P) dependent steroid dehydrogenase-like
PCDH7 protocadherin 7
PLAU plasminogen activator, urokinase
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SCGB1D2 secretoglobin, family 1D, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SOX9 SRY (sex determining region Y)-box 9
SPDEF SAM pointed domain containing ETS transcription factor
TBL1X transducin (beta)-like 1X-linked
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRH thyrotropin-releasing hormone
TSKU tsukushi, small leucine rich proteoglycan
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
CCDC85B coiled-coil domain containing 85B
CCND1 cyclin D1
CXADR coxsackie virus and adenovirus receptor
CYFIP2 cytoplasmic FMR1 interacting protein 2
EIF5A eukaryotic translation initiation factor 5A
F12 coagulation factor XII (Hageman factor)
GAS1 growth arrest-specific 1
GDF15 growth differentiation factor 15
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPI glucose-6-phosphate isomerase
GREM1 gremlin 1, DAN family BMP antagonist
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HOPX HOP homeobox
HOXA5 homeobox A5
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
KDM5D lysine (K)-specific demethylase 5D
KIAA0125 KIAA0125
KLK5 kallikrein-related peptidase 5
LEF1 lymphoid enhancer-binding factor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
OXTR oxytocin receptor
PDLIM2 PDZ and LIM domain 2 (mystique)
REXO2 RNA exonuclease 2
RPL31 ribosomal protein L31
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
ST7 suppression of tumorigenicity 7
STEAP1 six transmembrane epithelial antigen of the prostate 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM97 transmembrane protein 97
TSPYL5 TSPY-like 5
TYRP1 tyrosinase-related protein 1
YBX3 Y box binding protein 3