BRD-K06712146_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K06712146_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
BHLHE41 basic helix-loop-helix family, member e41
BLNK B-cell linker
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CPA3 carboxypeptidase A3 (mast cell)
CYBB cytochrome b-245, beta polypeptide
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
GDF15 growth differentiation factor 15
MKRN1 makorin ring finger protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RND3 Rho family GTPase 3
SMAD3 SMAD family member 3
STC2 stanniocalcin 2
SULF1 sulfatase 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AQP3 aquaporin 3 (Gill blood group)
BCHE butyrylcholinesterase
CKS2 CDC28 protein kinase regulatory subunit 2
CXCL8 chemokine (C-X-C motif) ligand 8
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GNAS GNAS complex locus
GPX3 glutathione peroxidase 3
H2AFV H2A histone family, member V
HOPX HOP homeobox
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
MT1E metallothionein 1E
MT1F metallothionein 1F
POSTN periostin, osteoblast specific factor
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SPINK5 serine peptidase inhibitor, Kazal type 5
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10