BRD-K06436323_3-ethyl-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-2,4(1H,3H)-dione_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K06436323_3-ethyl-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-2,4(1H,3H)-dione_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AGR2 anterior gradient 2
CA12 carbonic anhydrase XII
CTTN cortactin
FHL1 four and a half LIM domains 1
GLRX glutaredoxin (thioltransferase)
HOXB7 homeobox B7
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LINC00341 long intergenic non-protein coding RNA 341
NRN1 neuritin 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

decreased expression

Symbol Name
CDC45 cell division cycle 45
DKK3 dickkopf WNT signaling pathway inhibitor 3
GATA6 GATA binding protein 6
IFITM1 interferon induced transmembrane protein 1
IGFBP7 insulin-like growth factor binding protein 7
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
KAZN kazrin, periplakin interacting protein
MYBPC1 myosin binding protein C, slow type
PLK2 polo-like kinase 2
RNF167 ring finger protein 167