BRD-K05870596_XMD-1499_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K05870596_XMD-1499_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AQP3 aquaporin 3 (Gill blood group)
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
CCND2 cyclin D2
CNOT4 CCR4-NOT transcription complex, subunit 4
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
EIF5A eukaryotic translation initiation factor 5A
FKBP14 FK506 binding protein 14, 22 kDa
FOLR1 folate receptor 1 (adult)
GARS glycyl-tRNA synthetase
GDF15 growth differentiation factor 15
HSPA13 heat shock protein 70kDa family, member 13
IFRD2 interferon-related developmental regulator 2
IL6ST interleukin 6 signal transducer
NFE2L2 nuclear factor, erythroid 2-like 2
NPY1R neuropeptide Y receptor Y1
NRCAM neuronal cell adhesion molecule
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PSAT1 phosphoserine aminotransferase 1
PYCR1 pyrroline-5-carboxylate reductase 1
RAD51C RAD51 paralog C
RBP1 retinol binding protein 1, cellular
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORBS3 sorbin and SH3 domain containing 3
SSFA2 sperm specific antigen 2
SYBU syntabulin (syntaxin-interacting)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)

decreased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
AMIGO2 adhesion molecule with Ig-like domain 2
CA9 carbonic anhydrase IX
CCL2 chemokine (C-C motif) ligand 2
CD24 CD24 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL1A2 collagen, type I, alpha 2
CREB1 cAMP responsive element binding protein 1
CXCL11 chemokine (C-X-C motif) ligand 11
FCGBP Fc fragment of IgG binding protein
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP2 guanylate binding protein 2, interferon-inducible
GPRC5B G protein-coupled receptor, class C, group 5, member B
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IPO13 importin 13
JCHAIN joining chain of multimeric IgA and IgM
KIAA1598
MXRA5 matrix-remodelling associated 5
PLA2G16 phospholipase A2, group XVI
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMM2 phosphomannomutase 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
TAGLN2 transgelin 2
TM9SF3 transmembrane 9 superfamily member 3
VTCN1 V-set domain containing T cell activation inhibitor 1
ZNF589 zinc finger protein 589