BRD-K05804044_AZ-628_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

19 genes differentially expressed following the BRD-K05804044_AZ-628_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
GADD45B growth arrest and DNA-damage-inducible, beta
JUN jun proto-oncogene
LTBP2 latent transforming growth factor beta binding protein 2
NREP neuronal regeneration related protein
PALLD palladin, cytoskeletal associated protein
PDGFA platelet-derived growth factor alpha polypeptide
PXDN peroxidasin
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SRGN serglycin
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CXCL5 chemokine (C-X-C motif) ligand 5
NR2F1 nuclear receptor subfamily 2, group F, member 1
PRKCH protein kinase C, eta
RGS2 regulator of G-protein signaling 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TSPAN8 tetraspanin 8