BRD-K05673000_Dicloxacillin sodium salt hydrate_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K05673000_Dicloxacillin sodium salt hydrate_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ARL4C ADP-ribosylation factor-like 4C
CADM1 cell adhesion molecule 1
CCND2 cyclin D2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL11A1 collagen, type XI, alpha 1
COL3A1 collagen, type III, alpha 1
CTNND1 catenin (cadherin-associated protein), delta 1
DOK5 docking protein 5
ELANE elastase, neutrophil expressed
FAM129A family with sequence similarity 129, member A
GTPBP8 GTP-binding protein 8 (putative)
HDAC9 histone deacetylase 9
HIST1H1C histone cluster 1, H1c
IER5 immediate early response 5
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
MEF2C myocyte enhancer factor 2C
PPIB peptidylprolyl isomerase B (cyclophilin B)
RBP1 retinol binding protein 1, cellular
S100A8 S100 calcium binding protein A8
SULF1 sulfatase 1
TM4SF1 transmembrane 4 L six family member 1
TPBG trophoblast glycoprotein
UBQLN2 ubiquilin 2
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
APOD apolipoprotein D
BASP1 brain abundant, membrane attached signal protein 1
CCL5 chemokine (C-C motif) ligand 5
CD81 CD81 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHRDL1 chordin-like 1
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
ELF1 E74-like factor 1 (ets domain transcription factor)
F3 coagulation factor III (thromboplastin, tissue factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
GHR growth hormone receptor
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPX3 glutathione peroxidase 3
IGF1R insulin-like growth factor 1 receptor
IGKV1-5 immunoglobulin kappa variable 1-5
IRS2 insulin receptor substrate 2
KANK2 KN motif and ankyrin repeat domains 2
LUC7L3 LUC7-like 3 (S. cerevisiae)
MALT1 MALT1 paracaspase
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MGLL monoglyceride lipase
PLK1 polo-like kinase 1
SFN stratifin
SFPQ splicing factor proline/glutamine-rich
SKP1 S-phase kinase-associated protein 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNGR3 synaptogyrin 3
TATDN2 TatD DNase domain containing 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGM2 transglutaminase 2
TOP1 topoisomerase (DNA) I
TSPAN13 tetraspanin 13