BRD-K05326558_2-(1,3-Dimethyl-2,6-dioxo-7-propyl-2,3,6,7-tetrahydro-1H-purin-8-ylsulfanyl)-N-(4,5,6,7-tetrahydro-benzothiazol-2-yl)-acetamide_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K05326558_2-(1,3-Dimethyl-2,6-dioxo-7-propyl-2,3,6,7-tetrahydro-1H-purin-8-ylsulfanyl)-N-(4,5,6,7-tetrahydro-benzothiazol-2-yl)-acetamide_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C3ORF14 chromosome 3 open reading frame 14
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPE carboxypeptidase E
GMPR guanosine monophosphate reductase
IFI6 interferon, alpha-inducible protein 6
NEFH neurofilament, heavy polypeptide
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SLC38A1 solute carrier family 38, member 1
SYT1 synaptotagmin I
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ANKRD28 ankyrin repeat domain 28
AQP3 aquaporin 3 (Gill blood group)
CTSH cathepsin H
DUSP22 dual specificity phosphatase 22
EMP3 epithelial membrane protein 3
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FASTKD5 FAST kinase domains 5
GNAS GNAS complex locus
GPRC5A G protein-coupled receptor, class C, group 5, member A
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LAMA3 laminin, alpha 3
LAMP1 lysosomal-associated membrane protein 1
MBNL1 muscleblind-like splicing regulator 1
S100A10 S100 calcium binding protein A10
S100A7 S100 calcium binding protein A7
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SSFA2 sperm specific antigen 2