BRD-K05104363_PD-184352_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

115 genes differentially expressed following the BRD-K05104363_PD-184352_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADGRG1 adhesion G protein-coupled receptor G1
AHNAK AHNAK nucleoprotein
ANXA4 annexin A4
ASS1 argininosuccinate synthase 1
C1ORF115 chromosome 1 open reading frame 115
CD99 CD99 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COL4A1 collagen, type IV, alpha 1
CRYAB crystallin, alpha B
CXCL14 chemokine (C-X-C motif) ligand 14
DSP desmoplakin
EFNA1 ephrin-A1
EGFL6 EGF-like-domain, multiple 6
ERBB2 erb-b2 receptor tyrosine kinase 2
FAM134B family with sequence similarity 134, member B
FNBP1 formin binding protein 1
FOLR1 folate receptor 1 (adult)
GADD45B growth arrest and DNA-damage-inducible, beta
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IL32 interleukin 32
ISG15 ISG15 ubiquitin-like modifier
JAK1 Janus kinase 1
KIAA1598
KLF4 Kruppel-like factor 4 (gut)
KRT5 keratin 5, type II
LAMA3 laminin, alpha 3
LOX lysyl oxidase
LPL lipoprotein lipase
MAP7 microtubule-associated protein 7
NDRG1 N-myc downstream regulated 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDZK1IP1 PDZK1 interacting protein 1
PHYH phytanoyl-CoA 2-hydroxylase
PRUNE2 prune homolog 2 (Drosophila)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PXDN peroxidasin
RHOC ras homolog family member C
S100A10 S100 calcium binding protein A10
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIDT2 SID1 transmembrane family, member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TAGLN2 transgelin 2
TCEAL2 transcription elongation factor A (SII)-like 2
TRIM36 tripartite motif containing 36
TTC39A tetratricopeptide repeat domain 39A
TXNIP thioredoxin interacting protein
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADAM28 ADAM metallopeptidase domain 28
ADRB2 adrenoceptor beta 2, surface
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AREG amphiregulin
C7 complement component 7
CCND1 cyclin D1
CD24 CD24 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DCBLD2 discoidin, CUB and LCCL domain containing 2
DEFA4 defensin, alpha 4, corticostatin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHA2 EPH receptor A2
EREG epiregulin
ETV1 ets variant 1
ETV5 ets variant 5
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GOLT1B golgi transport 1B
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOPX HOP homeobox
HP haptoglobin
IER3 immediate early response 3
IRS1 insulin receptor substrate 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLK11 kallikrein-related peptidase 11
KRT13 keratin 13, type I
MAPK13 mitogen-activated protein kinase 13
MICB MHC class I polypeptide-related sequence B
MUC5B mucin 5B, oligomeric mucus/gel-forming
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NT5E 5'-nucleotidase, ecto (CD73)
PDE4B phosphodiesterase 4B, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK2 polo-like kinase 2
RBPMS RNA binding protein with multiple splicing
RGS2 regulator of G-protein signaling 2
SFRP1 secreted frizzled-related protein 1
SLC38A1 solute carrier family 38, member 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR3 small proline-rich protein 3
SPRY2 sprouty homolog 2 (Drosophila)
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TREM1 triggering receptor expressed on myeloid cells 1
TSPAN5 tetraspanin 5
TYMS thymidylate synthetase