BRD-K04887706_AKT-inhibitor-1-2_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K04887706_AKT-inhibitor-1-2_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASS1 argininosuccinate synthase 1
CAV1 caveolin 1, caveolae protein, 22kDa
CD200 CD200 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CHN1 chimerin 1
COMP cartilage oligomeric matrix protein
CPE carboxypeptidase E
CST7 cystatin F (leukocystatin)
CSTA cystatin A (stefin A)
DCN decorin
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
ELN elastin
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1R2 interleukin 1 receptor, type II
KIF5C kinesin family member 5C
LCN2 lipocalin 2
LUM lumican
MXRA7 matrix-remodelling associated 7
NINJ2 ninjurin 2
NPTX2 neuronal pentraxin II
OAT ornithine aminotransferase
PRAF2 PRA1 domain family, member 2
PRUNE2 prune homolog 2 (Drosophila)
RGS1 regulator of G-protein signaling 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STK39 serine threonine kinase 39
TES testin LIM domain protein
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
VTCN1 V-set domain containing T cell activation inhibitor 1
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AHNAK AHNAK nucleoprotein
AQP3 aquaporin 3 (Gill blood group)
CA12 carbonic anhydrase XII
CAST calpastatin
CDC25B cell division cycle 25B
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CTNND1 catenin (cadherin-associated protein), delta 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FMO2 flavin containing monooxygenase 2 (non-functional)
GRB14 growth factor receptor-bound protein 14
IGHM immunoglobulin heavy constant mu
KDM5D lysine (K)-specific demethylase 5D
NES nestin
NPY1R neuropeptide Y receptor Y1
NRP1 neuropilin 1
PARD3 par-3 family cell polarity regulator
PBX1 pre-B-cell leukemia homeobox 1
PDZK1 PDZ domain containing 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
SALL1 spalt-like transcription factor 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
SRRM2 serine/arginine repetitive matrix 2
TPBG trophoblast glycoprotein
TTC3 tetratricopeptide repeat domain 3
ZFP36L1 ZFP36 ring finger protein-like 1