BRD-K04887706_AKT-inhibitor-1-2_HS578T_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K04887706_AKT-inhibitor-1-2_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHR aryl hydrocarbon receptor
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CHL1 cell adhesion molecule L1-like
CHRDL1 chordin-like 1
CLEC2B C-type lectin domain family 2, member B
CXCL5 chemokine (C-X-C motif) ligand 5
FABP4 fatty acid binding protein 4, adipocyte
FLRT2 fibronectin leucine rich transmembrane protein 2
GPM6B glycoprotein M6B
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
ISYNA1 inositol-3-phosphate synthase 1
KRT19 keratin 19, type I
LAMA4 laminin, alpha 4
LTBP1 latent transforming growth factor beta binding protein 1
MAOA monoamine oxidase A
MEOX2 mesenchyme homeobox 2
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MSMO1 methylsterol monooxygenase 1
NEFL neurofilament, light polypeptide
PEG3 paternally expressed 3
QPCT glutaminyl-peptide cyclotransferase
SKAP2 src kinase associated phosphoprotein 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TFPI2 tissue factor pathway inhibitor 2
TRIB2 tribbles pseudokinase 2
VGLL4 vestigial-like family member 4
VWF von Willebrand factor
WASF3 WAS protein family, member 3
XYLT1 xylosyltransferase I

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
AMD1 adenosylmethionine decarboxylase 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CALML4 calmodulin-like 4
CLIC3 chloride intracellular channel 3
CRIP1 cysteine-rich protein 1 (intestinal)
DEGS1 delta(4)-desaturase, sphingolipid 1
FZD7 frizzled class receptor 7
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
KLK10 kallikrein-related peptidase 10
KLK6 kallikrein-related peptidase 6
LOC100505650 uncharacterized LOC100505650
MYRF myelin regulatory factor
NEB nebulin
PHLDA2 pleckstrin homology-like domain, family A, member 2
RAB40B RAB40B, member RAS oncogene family
S100A12 S100 calcium binding protein A12
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SPRR1A small proline-rich protein 1A
TARP TCR gamma alternate reading frame protein