BRD-K04887706_AKT-inhibitor-1-2_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K04887706_AKT-inhibitor-1-2_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CD81 CD81 molecule
CD9 CD9 molecule
CHL1 cell adhesion molecule L1-like
CLU clusterin
ESR1 estrogen receptor 1
FN1 fibronectin 1
IFI27 interferon, alpha-inducible protein 27
KLRK1 killer cell lectin-like receptor subfamily K, member 1
MATN2 matrilin 2
MYRF myelin regulatory factor
PEG3 paternally expressed 3
PRAME preferentially expressed antigen in melanoma
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SEPP1 selenoprotein P, plasma, 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SRRM2 serine/arginine repetitive matrix 2
TUBA1A tubulin, alpha 1a
VNN1 vanin 1

decreased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
COL5A1 collagen, type V, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
MDFIC MyoD family inhibitor domain containing
MFAP5 microfibrillar associated protein 5
OLFM4 olfactomedin 4
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SFRP4 secreted frizzled-related protein 4