BRD-K04695623_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K04695623_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ANOS1 anosmin 1
CCL5 chemokine (C-C motif) ligand 5
CLIC4 chloride intracellular channel 4
CREB3L2 cAMP responsive element binding protein 3-like 2
DDIT4 DNA-damage-inducible transcript 4
DPYSL3 dihydropyrimidinase-like 3
FAM129A family with sequence similarity 129, member A
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
ITM2A integral membrane protein 2A
KDM5D lysine (K)-specific demethylase 5D
KYNU kynureninase
LMO3 LIM domain only 3 (rhombotin-like 2)
MAGT1 magnesium transporter 1
MAP7 microtubule-associated protein 7
MYO10 myosin X
NELL2 NEL-like 2 (chicken)
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NUPR1 nuclear protein, transcriptional regulator, 1
PLXNC1 plexin C1
PON3 paraoxonase 3
PTN pleiotrophin
RGS1 regulator of G-protein signaling 1
RPL38 ribosomal protein L38
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPT10 septin 10
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TMEM255A transmembrane protein 255A
USP6NL USP6 N-terminal like
VLDLR very low density lipoprotein receptor
WFDC1 WAP four-disulfide core domain 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
AOX1 aldehyde oxidase 1
APOD apolipoprotein D
AREG amphiregulin
CRYAB crystallin, alpha B
CTTN cortactin
DKK1 dickkopf WNT signaling pathway inhibitor 1
F13A1 coagulation factor XIII, A1 polypeptide
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
FLRT3 fibronectin leucine rich transmembrane protein 3
G0S2 G0/G1 switch 2
HMGA1 high mobility group AT-hook 1
IFI6 interferon, alpha-inducible protein 6
IGFBP4 insulin-like growth factor binding protein 4
KCTD12 potassium channel tetramerization domain containing 12
KRT14 keratin 14, type I
KRT19 keratin 19, type I
LAMC1 laminin, gamma 1 (formerly LAMB2)
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MGP matrix Gla protein
MT1X metallothionein 1X
NFIB nuclear factor I/B
ODC1 ornithine decarboxylase 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
POSTN periostin, osteoblast specific factor
PRR7 proline rich 7 (synaptic)
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A2 S100 calcium binding protein A2
SCG5 secretogranin V
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
ZNF586 zinc finger protein 586