BRD-K04430056_-666_MCF7_24.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K04430056_-666_MCF7_24.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CLU clusterin
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
FHOD3 formin homology 2 domain containing 3
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
PIR pirin (iron-binding nuclear protein)
RAP1GAP RAP1 GTPase activating protein
SCPEP1 serine carboxypeptidase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSKU tsukushi, small leucine rich proteoglycan
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CLDN10 claudin 10
DCN decorin
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MGP matrix Gla protein
MUC1 mucin 1, cell surface associated
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PTTG1 pituitary tumor-transforming 1
RAB31 RAB31, member RAS oncogene family
RGS4 regulator of G-protein signaling 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPON1 spondin 1, extracellular matrix protein
TMSB15A thymosin beta 15a