BRD-K04414442_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K04414442_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ARMCX6 armadillo repeat containing, X-linked 6
ASNS asparagine synthetase (glutamine-hydrolyzing)
C10ORF10 chromosome 10 open reading frame 10
CPM carboxypeptidase M
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GIMAP4 GTPase, IMAP family member 4
HMG20B high mobility group 20B
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KDM5D lysine (K)-specific demethylase 5D
KRT14 keratin 14, type I
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K3 mitogen-activated protein kinase kinase 3
RBPMS RNA binding protein with multiple splicing
SFTPB surfactant protein B
SMYD3 SET and MYND domain containing 3
SNX11 sorting nexin 11
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSPAN7 tetraspanin 7
VAV3 vav 3 guanine nucleotide exchange factor
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
AOX1 aldehyde oxidase 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL6 B-cell CLL/lymphoma 6
CA2 carbonic anhydrase II
CCK cholecystokinin
CD24 CD24 molecule
CDV3 CDV3 homolog (mouse)
CLIC4 chloride intracellular channel 4
CXCL12 chemokine (C-X-C motif) ligand 12
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A eukaryotic translation initiation factor 5A
EREG epiregulin
F3 coagulation factor III (thromboplastin, tissue factor)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
IFRD2 interferon-related developmental regulator 2
KRT8 keratin 8, type II
MAP7 microtubule-associated protein 7
NEBL nebulette
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAWR PRKC, apoptosis, WT1, regulator
PAX5 paired box 5
PCSK1 proprotein convertase subtilisin/kexin type 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPRO protein tyrosine phosphatase, receptor type, O
RGCC regulator of cell cycle
RHOBTB3 Rho-related BTB domain containing 3
RNF167 ring finger protein 167
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SRSF6 serine/arginine-rich splicing factor 6
STX1A syntaxin 1A (brain)
TCL1A T-cell leukemia/lymphoma 1A
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
VCAN versican