BRD-K03642198_AY 9944_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K03642198_AY 9944_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAT1 adenosine deaminase, tRNA-specific 1
ADD3 adducin 3 (gamma)
ALDOC aldolase C, fructose-bisphosphate
APLP2 amyloid beta (A4) precursor-like protein 2
APOA1 apolipoprotein A-I
ATM ATM serine/threonine kinase
DARS aspartyl-tRNA synthetase
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK3 dickkopf WNT signaling pathway inhibitor 3
DSP desmoplakin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
FABP1 fatty acid binding protein 1, liver
FAM171A1 family with sequence similarity 171, member A1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FOLR1 folate receptor 1 (adult)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
KDM5D lysine (K)-specific demethylase 5D
KLF6 Kruppel-like factor 6
LPIN1 lipin 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MDK midkine (neurite growth-promoting factor 2)
METTL7A methyltransferase like 7A
MME membrane metallo-endopeptidase
MSMO1 methylsterol monooxygenase 1
MTSS1 metastasis suppressor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
OPTN optineurin
PCP4 Purkinje cell protein 4
PEG3 paternally expressed 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RBMS1 RNA binding motif, single stranded interacting protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB1D2 secretoglobin, family 1D, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SPINT2 serine peptidase inhibitor, Kunitz type, 2
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ZNF91 zinc finger protein 91
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
CD58 CD58 molecule
CDC42 cell division cycle 42
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHSY1 chondroitin sulfate synthase 1
EAF2 ELL associated factor 2
EIF5 eukaryotic translation initiation factor 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HOXC6 homeobox C6
MTERF3 mitochondrial transcription termination factor 3
NGRN neugrin, neurite outgrowth associated
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUSAP1 nucleolar and spindle associated protein 1
PLAC8 placenta-specific 8
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SNX10 sorting nexin 10
SORBS1 sorbin and SH3 domain containing 1
SPAG7 sperm associated antigen 7
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TMSB15A thymosin beta 15a
TRIB2 tribbles pseudokinase 2
WFS1 Wolfram syndrome 1 (wolframin)