BRD-K03449891_foretinib_BT20_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K03449891_foretinib_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
CTSB cathepsin B
DACH1 dachshund family transcription factor 1
GRB14 growth factor receptor-bound protein 14
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
NPDC1 neural proliferation, differentiation and control, 1
RBM47 RNA binding motif protein 47
RPL31 ribosomal protein L31
STK26 serine/threonine protein kinase 26
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNIP1 TNFAIP3 interacting protein 1
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ANXA3 annexin A3
C1S complement component 1, s subcomponent
CD200 CD200 molecule
CDC45 cell division cycle 45
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLTB clathrin, light chain B
COL15A1 collagen, type XV, alpha 1
COL8A2 collagen, type VIII, alpha 2
CSRP1 cysteine and glycine-rich protein 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
F3 coagulation factor III (thromboplastin, tissue factor)
FHL2 four and a half LIM domains 2
GADD45A growth arrest and DNA-damage-inducible, alpha
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ITM2A integral membrane protein 2A
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JUN jun proto-oncogene
KRT18 keratin 18, type I
MCM5 minichromosome maintenance complex component 5
MYL9 myosin, light chain 9, regulatory
NRN1 neuritin 1
PMP22 peripheral myelin protein 22
RANBP1 RAN binding protein 1
SDC2 syndecan 2
TPM1 tropomyosin 1 (alpha)
TSPAN8 tetraspanin 8
WNT5A wingless-type MMTV integration site family, member 5A
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta