BRD-K03406345_azacitidine_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K03406345_azacitidine_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CTGF connective tissue growth factor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FAM129A family with sequence similarity 129, member A
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GOLGA8A golgin A8 family, member A
GPX3 glutathione peroxidase 3
GPX4 glutathione peroxidase 4
HIST1H2BC histone cluster 1, H2bc
IFI6 interferon, alpha-inducible protein 6
IGL immunoglobulin lambda locus
ISG15 ISG15 ubiquitin-like modifier
MAGED1 melanoma antigen family D1
METRN meteorin, glial cell differentiation regulator
MFAP5 microfibrillar associated protein 5
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDE8B phosphodiesterase 8B
PEX11A peroxisomal biogenesis factor 11 alpha
PHGDH phosphoglycerate dehydrogenase
PLA2G16 phospholipase A2, group XVI
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POSTN periostin, osteoblast specific factor
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
SCD5 stearoyl-CoA desaturase 5
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SQSTM1 sequestosome 1
SULF1 sulfatase 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TOB1 transducer of ERBB2, 1
TPD52L1 tumor protein D52-like 1
VLDLR very low density lipoprotein receptor
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ALOX15B arachidonate 15-lipoxygenase, type B
ARG1 arginase 1
ASCL1 achaete-scute family bHLH transcription factor 1
CCNB1 cyclin B1
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
COL18A1 collagen, type XVIII, alpha 1
COPS7A COP9 signalosome subunit 7A
CORO1A coronin, actin binding protein, 1A
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DHRS1 dehydrogenase/reductase (SDR family) member 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBLN1 fibulin 1
FGFR3 fibroblast growth factor receptor 3
GPNMB glycoprotein (transmembrane) nmb
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HP haptoglobin
HSPB1 heat shock 27kDa protein 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
LOC100505650 uncharacterized LOC100505650
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
NEB nebulin
NEFH neurofilament, heavy polypeptide
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PON3 paraoxonase 3
PXMP2 peroxisomal membrane protein 2, 22kDa
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SPON2 spondin 2, extracellular matrix protein
TACSTD2 tumor-associated calcium signal transducer 2
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
XIST X inactive specific transcript (non-protein coding)