BRD-K03406345_azacitidine_A375_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

123 genes differentially expressed following the BRD-K03406345_azacitidine_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AIM2 absent in melanoma 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
C6ORF48 chromosome 6 open reading frame 48
CA2 carbonic anhydrase II
CBS cystathionine-beta-synthase
CCL19 chemokine (C-C motif) ligand 19
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFD complement factor D (adipsin)
CLDN7 claudin 7
CLGN calmegin
CSRP1 cysteine and glycine-rich protein 1
CTH cystathionine gamma-lyase
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL2 chemokine (C-X-C motif) ligand 2
DDIT4 DNA-damage-inducible transcript 4
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ERBB4 erb-b2 receptor tyrosine kinase 4
ESRP1 epithelial splicing regulatory protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
FBLN2 fibulin 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GREM1 gremlin 1, DAN family BMP antagonist
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HSPA9 heat shock 70kDa protein 9 (mortalin)
IARS isoleucyl-tRNA synthetase
IFI27 interferon, alpha-inducible protein 27
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFRD1 interferon-related developmental regulator 1
IGFBP3 insulin-like growth factor binding protein 3
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
INHBA inhibin, beta A
ISG15 ISG15 ubiquitin-like modifier
KRT14 keratin 14, type I
MFAP5 microfibrillar associated protein 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MME membrane metallo-endopeptidase
MOCOS molybdenum cofactor sulfurase
MT1M metallothionein 1M
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NKX3-1 NK3 homeobox 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRN1 neuritin 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFA platelet-derived growth factor alpha polypeptide
PER2 period circadian clock 2
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
PYCR1 pyrroline-5-carboxylate reductase 1
RSAD2 radical S-adenosyl methionine domain containing 2
S100P S100 calcium binding protein P
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SQSTM1 sequestosome 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STC2 stanniocalcin 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK26 serine/threonine protein kinase 26
SULF1 sulfatase 1
TARS threonyl-tRNA synthetase
TMEM47 transmembrane protein 47
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ASRGL1 asparaginase like 1
BAD BCL2-associated agonist of cell death
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCNG1 cyclin G1
CDC25B cell division cycle 25B
CKB creatine kinase, brain
CLIC3 chloride intracellular channel 3
COL4A2 collagen, type IV, alpha 2
COL9A3 collagen, type IX, alpha 3
CTSC cathepsin C
DLK1 delta-like 1 homolog (Drosophila)
DSTN destrin (actin depolymerizing factor)
FLRT3 fibronectin leucine rich transmembrane protein 3
GNAS GNAS complex locus
GREB1 growth regulation by estrogen in breast cancer 1
HIST1H2BG histone cluster 1, H2bg
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JADE2 jade family PHD finger 2
KIF20A kinesin family member 20A
LAMB1 laminin, beta 1
LYZ lysozyme
NID1 nidogen 1
NMU neuromedin U
PCSK6 proprotein convertase subtilisin/kexin type 6
PRKCA protein kinase C, alpha
RPL31 ribosomal protein L31
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RTN2 reticulon 2
S100A10 S100 calcium binding protein A10
S100A4 S100 calcium binding protein A4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
STMN1 stathmin 1
TXNDC9 thioredoxin domain containing 9
WNT5A wingless-type MMTV integration site family, member 5A