BRD-K03063480_PF-477736_MDAMB231_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K03063480_PF-477736_MDAMB231_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BASP1 brain abundant, membrane attached signal protein 1
CAV1 caveolin 1, caveolae protein, 22kDa
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COTL1 coactosin-like F-actin binding protein 1
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF5A eukaryotic translation initiation factor 5A
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ETV1 ets variant 1
FSCN1 fascin actin-bundling protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
IDI1 isopentenyl-diphosphate delta isomerase 1
KIF14 kinesin family member 14
MDK midkine (neurite growth-promoting factor 2)
NEFH neurofilament, heavy polypeptide
NFIL3 nuclear factor, interleukin 3 regulated
NR4A2 nuclear receptor subfamily 4, group A, member 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
POU4F1 POU class 4 homeobox 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
S100P S100 calcium binding protein P
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
STAR steroidogenic acute regulatory protein
TARP TCR gamma alternate reading frame protein
TFF3 trefoil factor 3 (intestinal)
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
ADRB2 adrenoceptor beta 2, surface
ALCAM activated leukocyte cell adhesion molecule
ANXA4 annexin A4
ASPN asporin
BMP4 bone morphogenetic protein 4
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
CYTL1 cytokine-like 1
DCT dopachrome tautomerase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FN1 fibronectin 1
FOXN3 forkhead box N3
FZD7 frizzled class receptor 7
GADD45B growth arrest and DNA-damage-inducible, beta
GNAS GNAS complex locus
GPX7 glutathione peroxidase 7
HAS2 hyaluronan synthase 2
HBB hemoglobin, beta
HOXA10 homeobox A10
KRT5 keratin 5, type II
LTF lactotransferrin
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1B microtubule-associated protein 1B
MFAP5 microfibrillar associated protein 5
MN1 meningioma (disrupted in balanced translocation) 1
MX2 MX dynamin-like GTPase 2
NGRN neugrin, neurite outgrowth associated
NME4 NME/NM23 nucleoside diphosphate kinase 4
PLAC8 placenta-specific 8
PLBD1 phospholipase B domain containing 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PRKCB protein kinase C, beta
PROM1 prominin 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
S100A7 S100 calcium binding protein A7
SEPP1 selenoprotein P, plasma, 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPRR1A small proline-rich protein 1A
TACC1 transforming, acidic coiled-coil containing protein 1
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C
TUBB2A tubulin, beta 2A class IIa
VCAN versican
VSNL1 visinin-like 1