BRD-K03063480_PF-477736_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K03063480_PF-477736_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCNG1 cyclin G1
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DAPK1 death-associated protein kinase 1
ENO1 enolase 1, (alpha)
ERAP2 endoplasmic reticulum aminopeptidase 2
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
GADD45A growth arrest and DNA-damage-inducible, alpha
GJA1 gap junction protein, alpha 1, 43kDa
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
INSM1 insulinoma-associated 1
IRS2 insulin receptor substrate 2
KRT18 keratin 18, type I
LAMP1 lysosomal-associated membrane protein 1
MAGEA3 melanoma antigen family A3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MICALL1 MICAL-like 1
MTSS1 metastasis suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NID2 nidogen 2 (osteonidogen)
NR4A2 nuclear receptor subfamily 4, group A, member 2
PLXNB2 plexin B2
PRUNE2 prune homolog 2 (Drosophila)
RPS27L ribosomal protein S27-like
RSRP1 arginine/serine-rich protein 1
SESN1 sestrin 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIP6 thyroid hormone receptor interactor 6
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADRB2 adrenoceptor beta 2, surface
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
C1S complement component 1, s subcomponent
CCL2 chemokine (C-C motif) ligand 2
CD59 CD59 molecule, complement regulatory protein
CDH3 cadherin 3, type 1, P-cadherin (placental)
CENPU centromere protein U
CNN3 calponin 3, acidic
CPB1 carboxypeptidase B1 (tissue)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FGF13 fibroblast growth factor 13
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GINS2 GINS complex subunit 2 (Psf2 homolog)
GPM6B glycoprotein M6B
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H4C histone cluster 1, H4c
HP haptoglobin
IFI27 interferon, alpha-inducible protein 27
IGFBP7 insulin-like growth factor binding protein 7
ISG15 ISG15 ubiquitin-like modifier
LTF lactotransferrin
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MT3 metallothionein 3
MX1 MX dynamin-like GTPase 1
PRAME preferentially expressed antigen in melanoma
PRDX2 peroxiredoxin 2
RBP1 retinol binding protein 1, cellular
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TAGLN transgelin
UGCG UDP-glucose ceramide glucosyltransferase
VCAM1 vascular cell adhesion molecule 1
ZIC1 Zic family member 1