BRD-K02708799_GSK-1059615_SKBR3_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K02708799_GSK-1059615_SKBR3_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ARG1 arginase 1
C10ORF10 chromosome 10 open reading frame 10
CD36 CD36 molecule (thrombospondin receptor)
EMX2 empty spiracles homeobox 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
GPNMB glycoprotein (transmembrane) nmb
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1C histone cluster 1, H1c
ISG15 ISG15 ubiquitin-like modifier
KLHL24 kelch-like family member 24
KLK6 kallikrein-related peptidase 6
LOC100505650 uncharacterized LOC100505650
MEF2C myocyte enhancer factor 2C
STAT1 signal transducer and activator of transcription 1, 91kDa

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
C1ORF54 chromosome 1 open reading frame 54
C1QA complement component 1, q subcomponent, A chain
CCND2 cyclin D2
CHGB chromogranin B
COL3A1 collagen, type III, alpha 1
DCN decorin
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
JADE2 jade family PHD finger 2
JUN jun proto-oncogene
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LDHB lactate dehydrogenase B
LGALS1 lectin, galactoside-binding, soluble, 1
LUM lumican
MAOA monoamine oxidase A
PCSK1 proprotein convertase subtilisin/kexin type 1
PDLIM4 PDZ and LIM domain 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTHLH parathyroid hormone-like hormone
PTP4A1 protein tyrosine phosphatase type IVA, member 1
S100A10 S100 calcium binding protein A10
SCG5 secretogranin V
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SNAP25 synaptosomal-associated protein, 25kDa
TFF1 trefoil factor 1
TOX thymocyte selection-associated high mobility group box
TRIB3 tribbles pseudokinase 3
TUSC3 tumor suppressor candidate 3