BRD-K02708799_GSK-1059615_SKBR3_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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59 genes differentially expressed following the BRD-K02708799_GSK-1059615_SKBR3_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
C5 complement component 5
CCL5 chemokine (C-C motif) ligand 5
CEMIP cell migration inducing protein, hyaluronan binding
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DSP desmoplakin
FAM129A family with sequence similarity 129, member A
FAS Fas cell surface death receptor
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
HCAR3 hydroxycarboxylic acid receptor 3
IFI44L interferon-induced protein 44-like
IFITM1 interferon induced transmembrane protein 1
ITM2A integral membrane protein 2A
KRT15 keratin 15, type I
NELL2 NEL-like 2 (chicken)
OLFM1 olfactomedin 1
PDGFD platelet derived growth factor D
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SFTPA2 surfactant protein A2
SFTPC surfactant protein C
SLAMF7 SLAM family member 7
SLPI secretory leukocyte peptidase inhibitor
SPINK5 serine peptidase inhibitor, Kazal type 5
TFPI2 tissue factor pathway inhibitor 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TUBB2A tubulin, beta 2A class IIa
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCL vinculin
ZIC1 Zic family member 1

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
CDC20 cell division cycle 20
CDKN3 cyclin-dependent kinase inhibitor 3
CLDN3 claudin 3
COTL1 coactosin-like F-actin binding protein 1
CPB1 carboxypeptidase B1 (tissue)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELANE elastase, neutrophil expressed
ELOVL1 ELOVL fatty acid elongase 1
GATA6 GATA binding protein 6
HIST1H2BG histone cluster 1, H2bg
JADE2 jade family PHD finger 2
KRT6B keratin 6B, type II
PDZK1 PDZ domain containing 1
PLAT plasminogen activator, tissue
PMP22 peripheral myelin protein 22
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PROM1 prominin 1
SATB1 SATB homeobox 1
SFRP1 secreted frizzled-related protein 1
SHB Src homology 2 domain containing adaptor protein B
TMEM158 transmembrane protein 158 (gene/pseudogene)
ZNF91 zinc finger protein 91