BRD-K02708799_GSK-1059615_MCF7_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K02708799_GSK-1059615_MCF7_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKAP12 A kinase (PRKA) anchor protein 12
BASP1 brain abundant, membrane attached signal protein 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BPHL biphenyl hydrolase-like (serine hydrolase)
BTG1 B-cell translocation gene 1, anti-proliferative
CA12 carbonic anhydrase XII
COL4A5 collagen, type IV, alpha 5
CXCL3 chemokine (C-X-C motif) ligand 3
CYFIP2 cytoplasmic FMR1 interacting protein 2
ETV1 ets variant 1
FGFR3 fibroblast growth factor receptor 3
FOS FBJ murine osteosarcoma viral oncogene homolog
IGF1R insulin-like growth factor 1 receptor
IGHM immunoglobulin heavy constant mu
IL7R interleukin 7 receptor
LTBP1 latent transforming growth factor beta binding protein 1
MAP7 microtubule-associated protein 7
MYB v-myb avian myeloblastosis viral oncogene homolog
NRIP1 nuclear receptor interacting protein 1
PDE10A phosphodiesterase 10A
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RBPMS RNA binding protein with multiple splicing
RGS2 regulator of G-protein signaling 2
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC38A1 solute carrier family 38, member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SOX4 SRY (sex determining region Y)-box 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TSC22D1 TSC22 domain family, member 1
TSPAN12 tetraspanin 12
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
CD200 CD200 molecule
CHGB chromogranin B
CNOT2 CCR4-NOT transcription complex, subunit 2
COL15A1 collagen, type XV, alpha 1
CRYAB crystallin, alpha B
CTSZ cathepsin Z
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR2 early growth response 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GNAS GNAS complex locus
GOLGA8B golgin A8 family, member B
IFITM1 interferon induced transmembrane protein 1
JUN jun proto-oncogene
LAMC1 laminin, gamma 1 (formerly LAMB2)
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC283683 uncharacterized LOC283683
MMP7 matrix metallopeptidase 7
MT1X metallothionein 1X
PLAC8 placenta-specific 8
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TNC tenascin C
XIST X inactive specific transcript (non-protein coding)
ZEB2 zinc finger E-box binding homeobox 2