BRD-K02708799_GSK-1059615_MCF7_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K02708799_GSK-1059615_MCF7_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ANXA1 annexin A1
AUTS2 autism susceptibility candidate 2
C10ORF10 chromosome 10 open reading frame 10
CADM1 cell adhesion molecule 1
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
COL1A2 collagen, type I, alpha 2
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS3 dehydrogenase/reductase (SDR family) member 3
EAPP E2F-associated phosphoprotein
EGFR epidermal growth factor receptor
EPCAM epithelial cell adhesion molecule
EXPH5 exophilin 5
FBN2 fibrillin 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCLC glutamate-cysteine ligase, catalytic subunit
GPER1 G protein-coupled estrogen receptor 1
HIST1H2BG histone cluster 1, H2bg
IL1R2 interleukin 1 receptor, type II
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MXI1 MAX interactor 1, dimerization protein
PDE8A phosphodiesterase 8A
PLS1 plastin 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SCGB2A1 secretoglobin, family 2A, member 1
SFRP1 secreted frizzled-related protein 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPAG4 sperm associated antigen 4
TGFBI transforming growth factor, beta-induced, 68kDa
TXNIP thioredoxin interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADO 2-aminoethanethiol (cysteamine) dioxygenase
BST2 bone marrow stromal cell antigen 2
CHRDL1 chordin-like 1
CLU clusterin
CXCL13 chemokine (C-X-C motif) ligand 13
FABP4 fatty acid binding protein 4, adipocyte
FKBP14 FK506 binding protein 14, 22 kDa
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KRT7 keratin 7, type II
LAMP3 lysosomal-associated membrane protein 3
LDLR low density lipoprotein receptor
LPL lipoprotein lipase
MSMO1 methylsterol monooxygenase 1
NPY1R neuropeptide Y receptor Y1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGDS prostaglandin D2 synthase 21kDa (brain)
RPS11 ribosomal protein S11
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SUB1 SUB1 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TES testin LIM domain protein
TSPAN13 tetraspanin 13