BRD-K02708799_GSK-1059615_LNCAP_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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86 genes differentially expressed following the BRD-K02708799_GSK-1059615_LNCAP_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCK3 aarF domain containing kinase 3
ANKRD10 ankyrin repeat domain 10
ARHGAP32 Rho GTPase activating protein 32
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
CCL20 chemokine (C-C motif) ligand 20
COL9A2 collagen, type IX, alpha 2
CRABP2 cellular retinoic acid binding protein 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DNM1L dynamin 1-like
EIF3D eukaryotic translation initiation factor 3, subunit D
ENAH enabled homolog (Drosophila)
FAM129A family with sequence similarity 129, member A
FAM63A family with sequence similarity 63, member A
FOXG1 forkhead box G1
GATA3 GATA binding protein 3
GBP2 guanylate binding protein 2, interferon-inducible
HES1 hes family bHLH transcription factor 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITM2A integral membrane protein 2A
KDM3A lysine (K)-specific demethylase 3A
KIAA0907 KIAA0907
LPIN1 lipin 1
MAPK13 mitogen-activated protein kinase 13
MOXD1 monooxygenase, DBH-like 1
MT1M metallothionein 1M
MYO6 myosin VI
NEFL neurofilament, light polypeptide
PBX3 pre-B-cell leukemia homeobox 3
PPL periplakin
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC35E2B solute carrier family 35, member E2B
SOD2 superoxide dismutase 2, mitochondrial
SYNM synemin, intermediate filament protein
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
TXNL4B thioredoxin-like 4B
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ALCAM activated leukocyte cell adhesion molecule
C6ORF62 chromosome 6 open reading frame 62
CALB1 calbindin 1, 28kDa
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL3A1 collagen, type III, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DUSP14 dual specificity phosphatase 14
FGFR2 fibroblast growth factor receptor 2
FXYD2 FXYD domain containing ion transport regulator 2
GLS glutaminase
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
LDHB lactate dehydrogenase B
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LY75 lymphocyte antigen 75
MAT2A methionine adenosyltransferase II, alpha
MSMO1 methylsterol monooxygenase 1
MYH10 myosin, heavy chain 10, non-muscle
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPR3 natriuretic peptide receptor 3
NR4A3 nuclear receptor subfamily 4, group A, member 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PFN2 profilin 2
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PROM1 prominin 1
PRPF4 pre-mRNA processing factor 4
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RPL39L ribosomal protein L39-like
SACS sacsin molecular chaperone
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SRGN serglycin
SRI sorcin
TFF3 trefoil factor 3 (intestinal)
THBS1 thrombospondin 1
TYRP1 tyrosinase-related protein 1
UGCG UDP-glucose ceramide glucosyltransferase