BRD-K02708799_GSK-1059615_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K02708799_GSK-1059615_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AMDHD2 amidohydrolase domain containing 2
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
CAPN3 calpain 3, (p94)
CCNG2 cyclin G2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD99 CD99 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN2 chimerin 2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL11A1 collagen, type XI, alpha 1
CPE carboxypeptidase E
DAPK1 death-associated protein kinase 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOPX HOP homeobox
IGHM immunoglobulin heavy constant mu
ITGAV integrin, alpha V
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LPIN1 lipin 1
LRMP lymphoid-restricted membrane protein
MYBPC1 myosin binding protein C, slow type
N4BP2L2 NEDD4 binding protein 2-like 2
NUPR1 nuclear protein, transcriptional regulator, 1
OBSL1 obscurin-like 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLXNC1 plexin C1
PSAP prosaposin
SFTPA2 surfactant protein A2
SLC38A1 solute carrier family 38, member 1
SOX4 SRY (sex determining region Y)-box 4
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AREG amphiregulin
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AZU1 azurocidin 1
CCND1 cyclin D1
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLD dihydrolipoamide dehydrogenase
EFNB2 ephrin-B2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FLRT3 fibronectin leucine rich transmembrane protein 3
HSPA1A heat shock 70kDa protein 1A
IGLL1 immunoglobulin lambda-like polypeptide 1
JMJD6 jumonji domain containing 6
KLK10 kallikrein-related peptidase 10
KRT4 keratin 4, type II
LAMA3 laminin, alpha 3
LCN2 lipocalin 2
NAMPT nicotinamide phosphoribosyltransferase
NEFL neurofilament, light polypeptide
NR2F6 nuclear receptor subfamily 2, group F, member 6
PCDH9 protocadherin 9
PI3 peptidase inhibitor 3, skin-derived
PNP purine nucleoside phosphorylase
RGS4 regulator of G-protein signaling 4
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLIRP SRA stem-loop interacting RNA binding protein
SPRY2 sprouty homolog 2 (Drosophila)
TAGLN2 transgelin 2
TNC tenascin C
TPBG trophoblast glycoprotein
TXN thioredoxin
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)