BRD-K02708799_GSK-1059615_HME1_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K02708799_GSK-1059615_HME1_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AGR2 anterior gradient 2
AIM1 absent in melanoma 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ATF3 activating transcription factor 3
BTG1 B-cell translocation gene 1, anti-proliferative
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP1 dual specificity phosphatase 1
EAPP E2F-associated phosphoprotein
EGR1 early growth response 1
ETV1 ets variant 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GAS1 growth arrest-specific 1
GPER1 G protein-coupled estrogen receptor 1
HOXA5 homeobox A5
HOXC6 homeobox C6
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IGF1R insulin-like growth factor 1 receptor
IL6ST interleukin 6 signal transducer
KLF2 Kruppel-like factor 2
MDFIC MyoD family inhibitor domain containing
NID2 nidogen 2 (osteonidogen)
NMRK1 nicotinamide riboside kinase 1
NPTXR neuronal pentraxin receptor
NTS neurotensin
NUPR1 nuclear protein, transcriptional regulator, 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLA2G16 phospholipase A2, group XVI
PLS3 plastin 3
PNRC1 proline-rich nuclear receptor coactivator 1
PTN pleiotrophin
RAD21 RAD21 homolog (S. pombe)
RHOB ras homolog family member B
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
TBX3 T-box 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSC22D3 TSC22 domain family, member 3
VCAN versican
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
CCNE2 cyclin E2
CD93 CD93 molecule
CDC25A cell division cycle 25A
CHGB chromogranin B
CLIC5 chloride intracellular channel 5
CXCL14 chemokine (C-X-C motif) ligand 14
CYTL1 cytokine-like 1
FXYD3 FXYD domain containing ion transport regulator 3
GAL galanin/GMAP prepropeptide
GPX3 glutathione peroxidase 3
HBB hemoglobin, beta
HK2 hexokinase 2
IGL immunoglobulin lambda locus
IL1R2 interleukin 1 receptor, type II
JMJD6 jumonji domain containing 6
MAT2A methionine adenosyltransferase II, alpha
MN1 meningioma (disrupted in balanced translocation) 1
MSMO1 methylsterol monooxygenase 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NOP16 NOP16 nucleolar protein
PCP4 Purkinje cell protein 4
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PODXL podocalyxin-like
SLPI secretory leukocyte peptidase inhibitor
SPP1 secreted phosphoprotein 1
SV2C synaptic vesicle glycoprotein 2C
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM251 transmembrane protein 251