BRD-K02708799_GSK-1059615_BT20_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

115 genes differentially expressed following the BRD-K02708799_GSK-1059615_BT20_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ABHD4 abhydrolase domain containing 4
ADD3 adducin 3 (gamma)
ANKRD28 ankyrin repeat domain 28
ANKRD36B ankyrin repeat domain 36B
APOD apolipoprotein D
ARID5B AT rich interactive domain 5B (MRF1-like)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
C10ORF10 chromosome 10 open reading frame 10
C1S complement component 1, s subcomponent
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL20 chemokine (C-C motif) ligand 20
CD9 CD9 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CP ceruloplasmin (ferroxidase)
CRP C-reactive protein, pentraxin-related
DENND2D DENN/MADD domain containing 2D
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FGA fibrinogen alpha chain
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
GABARAPL1 GABA(A) receptor-associated protein like 1
GLUL glutamate-ammonia ligase
GOLGA8B golgin A8 family, member B
HIST1H1C histone cluster 1, H1c
HIST1H3H histone cluster 1, H3h
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL6ST interleukin 6 signal transducer
KIAA0907 KIAA0907
LCN2 lipocalin 2
LPAR6 lysophosphatidic acid receptor 6
LPIN2 lipin 2
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MKRN1 makorin ring finger protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
ORM1 orosomucoid 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKCA protein kinase C, alpha
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBP4 retinol binding protein 4, plasma
RPS4Y1 ribosomal protein S4, Y-linked 1
SCPEP1 serine carboxypeptidase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STC2 stanniocalcin 2
THBS2 thrombospondin 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC22D3 TSC22 domain family, member 3
TUSC3 tumor suppressor candidate 3
TXNIP thioredoxin interacting protein
VCAN versican
VNN1 vanin 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
AGRN agrin
CA2 carbonic anhydrase II
CD24 CD24 molecule
CXCR4 chemokine (C-X-C motif) receptor 4
DLD dihydrolipoamide dehydrogenase
DUSP4 dual specificity phosphatase 4
EAF2 ELL associated factor 2
EGR2 early growth response 2
EGR3 early growth response 3
EIF5 eukaryotic translation initiation factor 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FOSL1 FOS-like antigen 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HN1 hematological and neurological expressed 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
KRT7 keratin 7, type II
MALL mal, T-cell differentiation protein-like
MAT2A methionine adenosyltransferase II, alpha
MGLL monoglyceride lipase
NCK1 NCK adaptor protein 1
NDN necdin, melanoma antigen (MAGE) family member
OLFML2B olfactomedin-like 2B
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLK1 polo-like kinase 1
PODXL podocalyxin-like
PUF60 poly-U binding splicing factor 60KDa
RBP1 retinol binding protein 1, cellular
RFC2 replication factor C (activator 1) 2, 40kDa
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100P S100 calcium binding protein P
SLC43A3 solute carrier family 43, member 3
SOX9 SRY (sex determining region Y)-box 9
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TSPAN8 tetraspanin 8
VAMP8 vesicle-associated membrane protein 8