BRD-K02708799_GSK-1059615_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-K02708799_GSK-1059615_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMACR alpha-methylacyl-CoA racemase
APOD apolipoprotein D
AQP9 aquaporin 9
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
C10ORF10 chromosome 10 open reading frame 10
CAV1 caveolin 1, caveolae protein, 22kDa
CCL20 chemokine (C-C motif) ligand 20
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
COL1A1 collagen, type I, alpha 1
CP ceruloplasmin (ferroxidase)
CRIP2 cysteine-rich protein 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EGR1 early growth response 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
FAS Fas cell surface death receptor
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
GAS1 growth arrest-specific 1
GAS7 growth arrest-specific 7
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
HES1 hes family bHLH transcription factor 1
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGFBP1 insulin-like growth factor binding protein 1
IGFBP5 insulin-like growth factor binding protein 5
KLF4 Kruppel-like factor 4 (gut)
KLF9 Kruppel-like factor 9
LBH limb bud and heart development
LRRC17 leucine rich repeat containing 17
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP3 matrix metallopeptidase 3
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
PLAGL1 pleiomorphic adenoma gene-like 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLD3 phospholipase D family, member 3
PLTP phospholipid transfer protein
QKI QKI, KH domain containing, RNA binding
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SOD2 superoxide dismutase 2, mitochondrial
STEAP1 six transmembrane epithelial antigen of the prostate 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TXNIP thioredoxin interacting protein
VAV3 vav 3 guanine nucleotide exchange factor
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
C1ORF116 chromosome 1 open reading frame 116
CD24 CD24 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
FAM69A family with sequence similarity 69, member A
FCGBP Fc fragment of IgG binding protein
FOSL1 FOS-like antigen 1
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GPX2 glutathione peroxidase 2
HBB hemoglobin, beta
HBEGF heparin-binding EGF-like growth factor
HHEX hematopoietically expressed homeobox
HSPA8 heat shock 70kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
JMJD6 jumonji domain containing 6
LDLR low density lipoprotein receptor
LIMCH1 LIM and calponin homology domains 1
LYZ lysozyme
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAT2A methionine adenosyltransferase II, alpha
MNDA myeloid cell nuclear differentiation antigen
MTCL1 microtubule crosslinking factor 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PNP purine nucleoside phosphorylase
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLPI secretory leukocyte peptidase inhibitor
SNAP25 synaptosomal-associated protein, 25kDa
SPP1 secreted phosphoprotein 1
SRGN serglycin
SRSF7 serine/arginine-rich splicing factor 7
TM4SF1 transmembrane 4 L six family member 1
TPD52 tumor protein D52
TRIB3 tribbles pseudokinase 3
ZDHHC6 zinc finger, DHHC-type containing 6