BRD-K02708799_GSK-1059615_BT20_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K02708799_GSK-1059615_BT20_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARMCX1 armadillo repeat containing, X-linked 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BST2 bone marrow stromal cell antigen 2
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
C1ORF106 chromosome 1 open reading frame 106
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFB complement factor B
CYTH1 cytohesin 1
DEFB1 defensin, beta 1
ERBB3 erb-b2 receptor tyrosine kinase 3
F13A1 coagulation factor XIII, A1 polypeptide
FAM63A family with sequence similarity 63, member A
FOXO4 forkhead box O4
GREB1 growth regulation by estrogen in breast cancer 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HDAC5 histone deacetylase 5
HECA headcase homolog (Drosophila)
HIST1H2AC histone cluster 1, H2ac
HIST2H2BE histone cluster 2, H2be
HNMT histamine N-methyltransferase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
INSR insulin receptor
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MECOM MDS1 and EVI1 complex locus
METTL7A methyltransferase like 7A
MTSS1 metastasis suppressor 1
OBSL1 obscurin-like 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLAC8 placenta-specific 8
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POSTN periostin, osteoblast specific factor
PYCARD PYD and CARD domain containing
QPRT quinolinate phosphoribosyltransferase
RAB31 RAB31, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBP1 retinol binding protein 1, cellular
RBPMS RNA binding protein with multiple splicing
RSRP1 arginine/serine-rich protein 1
RTN2 reticulon 2
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SMAD3 SMAD family member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPINK1 serine peptidase inhibitor, Kazal type 1
STON1 stonin 1
TMEM50A transmembrane protein 50A
TMSB15A thymosin beta 15a
TNS1 tensin 1
TSC22D3 TSC22 domain family, member 3
TSPAN6 tetraspanin 6
UGCG UDP-glucose ceramide glucosyltransferase
VTCN1 V-set domain containing T cell activation inhibitor 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ADM adrenomedullin
AK4 adenylate kinase 4
ANXA1 annexin A1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CCDC86 coiled-coil domain containing 86
CKB creatine kinase, brain
CYR61 cysteine-rich, angiogenic inducer, 61
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FAS Fas cell surface death receptor
GPI glucose-6-phosphate isomerase
HBB hemoglobin, beta
IGHD immunoglobulin heavy constant delta
INSIG1 insulin induced gene 1
KCTD12 potassium channel tetramerization domain containing 12
KLF4 Kruppel-like factor 4 (gut)
KRT18 keratin 18, type I
KRT6A keratin 6A, type II
LDHB lactate dehydrogenase B
LHFP lipoma HMGIC fusion partner
LIMCH1 LIM and calponin homology domains 1
LIPG lipase, endothelial
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
PFKP phosphofructokinase, platelet
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRY2 sprouty homolog 2 (Drosophila)