BRD-K02708799_GSK-1059615_A549_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-K02708799_GSK-1059615_A549_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL5 chemokine (C-C motif) ligand 5
DAPK1 death-associated protein kinase 1
MAPK13 mitogen-activated protein kinase 13
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PON2 paraoxonase 2
RAB4A RAB4A, member RAS oncogene family
TMSB15A thymosin beta 15a
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
CCL19 chemokine (C-C motif) ligand 19
EGR1 early growth response 1
EXOSC4 exosome component 4
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL2RG interleukin 2 receptor, gamma
INHBA inhibin, beta A
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
THBS2 thrombospondin 2