BRD-K02216544_3-cyclohexyl-6-[4-(2,3-dichlorophenyl)piperazin-1-yl]pyrimidine-2,4(1H,3H)-dione_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

36 genes differentially expressed following the BRD-K02216544_3-cyclohexyl-6-[4-(2,3-dichlorophenyl)piperazin-1-yl]pyrimidine-2,4(1H,3H)-dione_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
CCK cholecystokinin
CKB creatine kinase, brain
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GJA1 gap junction protein, alpha 1, 43kDa
KLF10 Kruppel-like factor 10
LCN2 lipocalin 2
MMP9 matrix metallopeptidase 9
ORM1 orosomucoid 1
PCDH7 protocadherin 7
PDZK1IP1 PDZK1 interacting protein 1
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
SELENBP1 selenium binding protein 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SGK1 serum/glucocorticoid regulated kinase 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SOX4 SRY (sex determining region Y)-box 4
SPARCL1 SPARC-like 1 (hevin)

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
CDC25B cell division cycle 25B
IGFBP4 insulin-like growth factor binding protein 4
IGFBP6 insulin-like growth factor binding protein 6
JADE2 jade family PHD finger 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LYST lysosomal trafficking regulator
NT5E 5'-nucleotidase, ecto (CD73)
RNMT RNA (guanine-7-) methyltransferase
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SRGN serglycin
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TFPI2 tissue factor pathway inhibitor 2
ZMIZ1 zinc finger, MIZ-type containing 1