BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_VCAP_24.0_h_160.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_VCAP_24.0_h_160.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
AGTR1 angiotensin II receptor, type 1
AIM1 absent in melanoma 1
ANKRD10 ankyrin repeat domain 10
APOD apolipoprotein D
C16ORF45 chromosome 16 open reading frame 45
CCNG2 cyclin G2
CDK19 cyclin-dependent kinase 19
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGF13 fibroblast growth factor 13
FOXO4 forkhead box O4
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MARCKSL1 MARCKS-like 1
MSMO1 methylsterol monooxygenase 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERINC5 serine incorporator 5
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SQLE squalene epoxidase
TFF1 trefoil factor 1
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
BZW2 basic leucine zipper and W2 domains 2
C1QA complement component 1, q subcomponent, A chain
CDC25A cell division cycle 25A
CDC45 cell division cycle 45
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
EGFR epidermal growth factor receptor
EIF5A eukaryotic translation initiation factor 5A
FGFR3 fibroblast growth factor receptor 3
GSTP1 glutathione S-transferase pi 1
GUSBP11 glucuronidase, beta pseudogene 11
HHEX hematopoietically expressed homeobox
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOPX HOP homeobox
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MT1E metallothionein 1E
POSTN periostin, osteoblast specific factor
RRM2 ribonucleotide reductase M2
TMEM176B transmembrane protein 176B
WARS tryptophanyl-tRNA synthetase
XIST X inactive specific transcript (non-protein coding)