BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_HT29_24.0_h_160.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

104 genes differentially expressed following the BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_HT29_24.0_h_160.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP9A ATPase, class II, type 9A
BASP1 brain abundant, membrane attached signal protein 1
BCL6 B-cell CLL/lymphoma 6
BPIFA1 BPI fold containing family A, member 1
BTG1 B-cell translocation gene 1, anti-proliferative
C14ORF132 chromosome 14 open reading frame 132
CAPN2 calpain 2, (m/II) large subunit
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLDN10 claudin 10
CLIP3 CAP-GLY domain containing linker protein 3
CRISP3 cysteine-rich secretory protein 3
CTBP2 C-terminal binding protein 2
CTSB cathepsin B
CYBB cytochrome b-245, beta polypeptide
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DPYSL2 dihydropyrimidinase-like 2
DUSP3 dual specificity phosphatase 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FBN2 fibrillin 2
FDPS farnesyl diphosphate synthase
FOXO4 forkhead box O4
FSTL1 follistatin-like 1
FTH1 ferritin, heavy polypeptide 1
GAS6 growth arrest-specific 6
GLRX glutaredoxin (thioltransferase)
GPNMB glycoprotein (transmembrane) nmb
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INSIG1 insulin induced gene 1
IRF9 interferon regulatory factor 9
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
LDLR low density lipoprotein receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LY96 lymphocyte antigen 96
MLPH melanophilin
MME membrane metallo-endopeptidase
MVP major vault protein
MX1 MX dynamin-like GTPase 1
NDRG1 N-myc downstream regulated 1
NUPR1 nuclear protein, transcriptional regulator, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDE4C phosphodiesterase 4C, cAMP-specific
PID1 phosphotyrosine interaction domain containing 1
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAP1GAP RAP1 GTPase activating protein
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGK1 serum/glucocorticoid regulated kinase 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35E1 solute carrier family 35, member E1
SPDEF SAM pointed domain containing ETS transcription factor
SQLE squalene epoxidase
SQSTM1 sequestosome 1
TBL1X transducin (beta)-like 1X-linked
TOX thymocyte selection-associated high mobility group box
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TSPAN8 tetraspanin 8
TUBA1A tubulin, alpha 1a
VEGFA vascular endothelial growth factor A
VIM vimentin
WDTC1 WD and tetratricopeptide repeats 1
WNK1 WNK lysine deficient protein kinase 1
YPEL5 yippee-like 5 (Drosophila)
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
C1QBP complement component 1, q subcomponent binding protein
CD320 CD320 molecule
DLAT dihydrolipoamide S-acetyltransferase
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FAM46A family with sequence similarity 46, member A
GPX3 glutathione peroxidase 3
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPA4L heat shock 70kDa protein 4-like
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGLL1 immunoglobulin lambda-like polypeptide 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
LAMP1 lysosomal-associated membrane protein 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
ODC1 ornithine decarboxylase 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PEX3 peroxisomal biogenesis factor 3
PPIF peptidylprolyl isomerase F
PRMT1 protein arginine methyltransferase 1
RAD23B RAD23 homolog B (S. cerevisiae)
RPP40 ribonuclease P/MRP 40kDa subunit