BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_HEPG2_6.0_h_160.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

62 genes differentially expressed following the BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_HEPG2_6.0_h_160.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CES2 carboxylesterase 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
FADS1 fatty acid desaturase 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FHL1 four and a half LIM domains 1
FXYD3 FXYD domain containing ion transport regulator 3
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IL6ST interleukin 6 signal transducer
LAPTM4B lysosomal protein transmembrane 4 beta
MSMO1 methylsterol monooxygenase 1
MT1E metallothionein 1E
PSAP prosaposin
PTGES prostaglandin E synthase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TNS1 tensin 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ADAM28 ADAM metallopeptidase domain 28
AGR2 anterior gradient 2
AKR1C3 aldo-keto reductase family 1, member C3
CD24 CD24 molecule
CRIP1 cysteine-rich protein 1 (intestinal)
CRISP3 cysteine-rich secretory protein 3
CSRP1 cysteine and glycine-rich protein 1
CTGF connective tissue growth factor
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP2 dual specificity phosphatase 2
EPCAM epithelial cell adhesion molecule
FOSB FBJ murine osteosarcoma viral oncogene homolog B
HADH hydroxyacyl-CoA dehydrogenase
IER3 immediate early response 3
ITGB1BP1 integrin beta 1 binding protein 1
KDM5D lysine (K)-specific demethylase 5D
KRT19 keratin 19, type I
LTBP1 latent transforming growth factor beta binding protein 1
MAP7 microtubule-associated protein 7
MMP7 matrix metallopeptidase 7
MYB v-myb avian myeloblastosis viral oncogene homolog
PCP4 Purkinje cell protein 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
POSTN periostin, osteoblast specific factor
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SULF1 sulfatase 1
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TRAF5 TNF receptor-associated factor 5
WT1 Wilms tumor 1