BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_A375_6.0_h_160.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

21 genes differentially expressed following the BRD-K01868942_3-(piperidin-1-yl)propyl-4-amino-5-chloro-2methoxybenzoate . Hydrochloride_A375_6.0_h_160.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CCNG2 cyclin G2
DDIT4 DNA-damage-inducible transcript 4
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
MMP1 matrix metallopeptidase 1
MTSS1 metastasis suppressor 1
NUPR1 nuclear protein, transcriptional regulator, 1
PI3 peptidase inhibitor 3, skin-derived
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)

decreased expression

Symbol Name
AREG amphiregulin
COL4A6 collagen, type IV, alpha 6
GALC galactosylceramidase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
TMEM47 transmembrane protein 47