BRD-K01436366_XMD-1150_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-K01436366_XMD-1150_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADAMDEC1 ADAM-like, decysin 1
ALDOC aldolase C, fructose-bisphosphate
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
C3 complement component 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CIRBP cold inducible RNA binding protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR1 early growth response 1
FABP1 fatty acid binding protein 1, liver
FAM57A family with sequence similarity 57, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER5 immediate early response 5
MSLN mesothelin
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RGS2 regulator of G-protein signaling 2
RND3 Rho family GTPase 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SIK1 salt-inducible kinase 1
SLPI secretory leukocyte peptidase inhibitor
SNAP25 synaptosomal-associated protein, 25kDa
TFRC transferrin receptor
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TST thiosulfate sulfurtransferase (rhodanese)
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AKAP7 A kinase (PRKA) anchor protein 7
BGN biglycan
BHLHE41 basic helix-loop-helix family, member e41
C2CD2 C2 calcium-dependent domain containing 2
CA12 carbonic anhydrase XII
CBR3 carbonyl reductase 3
CCL2 chemokine (C-C motif) ligand 2
COL14A1 collagen, type XIV, alpha 1
COL5A1 collagen, type V, alpha 1
COMP cartilage oligomeric matrix protein
DHRS7 dehydrogenase/reductase (SDR family) member 7
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FLNB filamin B, beta
FRZB frizzled-related protein
GULP1 GULP, engulfment adaptor PTB domain containing 1
HES1 hes family bHLH transcription factor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
INHBA inhibin, beta A
ISLR immunoglobulin superfamily containing leucine-rich repeat
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JADE2 jade family PHD finger 2
JCHAIN joining chain of multimeric IgA and IgM
KLHL9 kelch-like family member 9
KRT14 keratin 14, type I
LAMB3 laminin, beta 3
LPAR6 lysophosphatidic acid receptor 6
LRRC32 leucine rich repeat containing 32
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MLPH melanophilin
MME membrane metallo-endopeptidase
MN1 meningioma (disrupted in balanced translocation) 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NKX3-1 NK3 homeobox 1
NPY1R neuropeptide Y receptor Y1
PENK proenkephalin
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PRKCH protein kinase C, eta
RASIP1 Ras interacting protein 1
RGS5 regulator of G-protein signaling 5
S100A12 S100 calcium binding protein A12
S100A2 S100 calcium binding protein A2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SORBS2 sorbin and SH3 domain containing 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STC2 stanniocalcin 2
SYNGR3 synaptogyrin 3
TACSTD2 tumor-associated calcium signal transducer 2
TFF3 trefoil factor 3 (intestinal)
THBD thrombomodulin
TM4SF1 transmembrane 4 L six family member 1
TSKU tsukushi, small leucine rich proteoglycan
XBP1 X-box binding protein 1