BRD-K01436366_XMD-1150_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

151 genes differentially expressed following the BRD-K01436366_XMD-1150_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BTBD3 BTB (POZ) domain containing 3
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COL9A1 collagen, type IX, alpha 1
CREG1 cellular repressor of E1A-stimulated genes 1
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
E2F2 E2F transcription factor 2
EFHC1 EF-hand domain (C-terminal) containing 1
EPS8 epidermal growth factor receptor pathway substrate 8
FAM46A family with sequence similarity 46, member A
FCGBP Fc fragment of IgG binding protein
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRZB frizzled-related protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA3 GATA binding protein 3
GPRC5B G protein-coupled receptor, class C, group 5, member B
GSTZ1 glutathione S-transferase zeta 1
H2BFS H2B histone family, member S (pseudogene)
HEBP1 heme binding protein 1
HIP1R huntingtin interacting protein 1 related
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
HPSE heparanase
INSM1 insulinoma-associated 1
KIF2C kinesin family member 2C
LGALS4 lectin, galactoside-binding, soluble, 4
MAN1C1 mannosidase, alpha, class 1C, member 1
MATN2 matrilin 2
MTSS1 metastasis suppressor 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
NELL2 NEL-like 2 (chicken)
NID2 nidogen 2 (osteonidogen)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OSBPL10 oxysterol binding protein-like 10
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSIP1 PC4 and SFRS1 interacting protein 1
PTCH1 patched 1
PXDN peroxidasin
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
REG1A regenerating islet-derived 1 alpha
SAT1 spermidine/spermine N1-acetyltransferase 1
SATB1 SATB homeobox 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SSFA2 sperm specific antigen 2
STK10 serine/threonine kinase 10
STXBP1 syntaxin binding protein 1
TBC1D31 TBC1 domain family, member 31
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIAM1 T-cell lymphoma invasion and metastasis 1
TMSB15A thymosin beta 15a
TXNIP thioredoxin interacting protein
VNN1 vanin 1
VWA5A von Willebrand factor A domain containing 5A
WDR19 WD repeat domain 19
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
AK4 adenylate kinase 4
ALCAM activated leukocyte cell adhesion molecule
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
APOD apolipoprotein D
BIRC3 baculoviral IAP repeat containing 3
C1ORF116 chromosome 1 open reading frame 116
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CD52 CD52 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CLDN8 claudin 8
COL1A1 collagen, type I, alpha 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTH1 cytohesin 1
ECM1 extracellular matrix protein 1
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EMP3 epithelial membrane protein 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FAIM Fas apoptotic inhibitory molecule
FAM129A family with sequence similarity 129, member A
FKBP14 FK506 binding protein 14, 22 kDa
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
GLIPR1 GLI pathogenesis-related 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXC6 homeobox C6
HSPE1 heat shock 10kDa protein 1
ICAM1 intercellular adhesion molecule 1
IFI44 interferon-induced protein 44
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IL32 interleukin 32
IL6 interleukin 6
INHBA inhibin, beta A
KRT19 keratin 19, type I
LIMCH1 LIM and calponin homology domains 1
LOX lysyl oxidase
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAL mal, T-cell differentiation protein
MAPK13 mitogen-activated protein kinase 13
MARCKS myristoylated alanine-rich protein kinase C substrate
MOK MOK protein kinase
MRPL15 mitochondrial ribosomal protein L15
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NME4 NME/NM23 nucleoside diphosphate kinase 4
NMI N-myc (and STAT) interactor
NOP16 NOP16 nucleolar protein
PLAT plasminogen activator, tissue
PLBD1 phospholipase B domain containing 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POSTN periostin, osteoblast specific factor
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PTX3 pentraxin 3, long
PYCR1 pyrroline-5-carboxylate reductase 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RGS4 regulator of G-protein signaling 4
S100A4 S100 calcium binding protein A4
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFN stratifin
SLPI secretory leukocyte peptidase inhibitor
SORBS3 sorbin and SH3 domain containing 3
STARD13 StAR-related lipid transfer (START) domain containing 13
STC2 stanniocalcin 2
TACSTD2 tumor-associated calcium signal transducer 2
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TPM1 tropomyosin 1 (alpha)
TUBB6 tubulin, beta 6 class V
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
VCAN versican
XBP1 X-box binding protein 1
ZBTB38 zinc finger and BTB domain containing 38