BRD-K01121114_AT-MLPCN CSC-006_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K01121114_AT-MLPCN CSC-006_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOLD1 apolipoprotein L domain containing 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPN asporin
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CARS cysteinyl-tRNA synthetase
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHN2 chimerin 2
CTGF connective tissue growth factor
CXCL2 chemokine (C-X-C motif) ligand 2
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DUSP5 dual specificity phosphatase 5
F3 coagulation factor III (thromboplastin, tissue factor)
FKBP11 FK506 binding protein 11, 19 kDa
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GARS glycyl-tRNA synthetase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
LDLR low density lipoprotein receptor
MARS methionyl-tRNA synthetase
MFAP5 microfibrillar associated protein 5
NARS asparaginyl-tRNA synthetase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFD platelet derived growth factor D
PER1 period circadian clock 1
PHGDH phosphoglycerate dehydrogenase
PLAU plasminogen activator, urokinase
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PSAT1 phosphoserine aminotransferase 1
REEP1 receptor accessory protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SNAI2 snail family zinc finger 2
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
XBP1 X-box binding protein 1
YARS tyrosyl-tRNA synthetase

decreased expression

Symbol Name
BMP2 bone morphogenetic protein 2
GPX3 glutathione peroxidase 3
HBE1 hemoglobin, epsilon 1
HSPA1A heat shock 70kDa protein 1A
LOC100505650 uncharacterized LOC100505650
NMU neuromedin U
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STX3 syntaxin 3
WNT5A wingless-type MMTV integration site family, member 5A