BRD-K00555438_2-Phenyl-quinoline-4-carboxylic acid [4-(thiazol-2-ylsulfamoyl)-phenyl]-amide MLS-0206672.0001_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K00555438_2-Phenyl-quinoline-4-carboxylic acid [4-(thiazol-2-ylsulfamoyl)-phenyl]-amide MLS-0206672.0001_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
CD14 CD14 molecule
CD163 CD163 molecule
FOSL1 FOS-like antigen 1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PPAP2B phosphatidic acid phosphatase type 2B
TKT transketolase
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ANXA3 annexin A3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
GREM1 gremlin 1, DAN family BMP antagonist
PCP4 Purkinje cell protein 4
PPARG peroxisome proliferator-activated receptor gamma
PRSS3 protease, serine, 3
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZBTB18 zinc finger and BTB domain containing 18