BRD-K00366212_2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-8-methoxyquinazolin-4-amine KUC106573N_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

25 genes differentially expressed following the BRD-K00366212_2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-8-methoxyquinazolin-4-amine KUC106573N_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CHI3L2 chitinase 3-like 2
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
PMP22 peripheral myelin protein 22
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBC1D31 TBC1 domain family, member 31
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
TRIB2 tribbles pseudokinase 2

decreased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
CCND2 cyclin D2
DKK3 dickkopf WNT signaling pathway inhibitor 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FILIP1L filamin A interacting protein 1-like
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
MDK midkine (neurite growth-promoting factor 2)
MSLN mesothelin
NT5E 5'-nucleotidase, ecto (CD73)
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RTN1 reticulon 1
SPINK1 serine peptidase inhibitor, Kazal type 1