BRD-A89352139_2-(5-Phenyl-2H-[1,2,4]triazol-3-yl)-3a,4,7,7a-tetrahydro-isoindole-1,3-dione_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A89352139_2-(5-Phenyl-2H-[1,2,4]triazol-3-yl)-3a,4,7,7a-tetrahydro-isoindole-1,3-dione_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BEX4 brain expressed, X-linked 4
CCND2 cyclin D2
CD200 CD200 molecule
CD93 CD93 molecule
COL6A2 collagen, type VI, alpha 2
COLEC12 collectin sub-family member 12
DKK3 dickkopf WNT signaling pathway inhibitor 3
ESM1 endothelial cell-specific molecule 1
FAM107A family with sequence similarity 107, member A
GJA1 gap junction protein, alpha 1, 43kDa
MMP9 matrix metallopeptidase 9
NID2 nidogen 2 (osteonidogen)
SCGB1D2 secretoglobin, family 1D, member 2
TMEM30B transmembrane protein 30B
TSPAN12 tetraspanin 12

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACSL1 acyl-CoA synthetase long-chain family member 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CA12 carbonic anhydrase XII
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
HOXA5 homeobox A5
KRT14 keratin 14, type I
KYNU kynureninase
LUC7L3 LUC7-like 3 (S. cerevisiae)
MMP7 matrix metallopeptidase 7
MTDH metadherin
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRDX1 peroxiredoxin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TOP1 topoisomerase (DNA) I