BRD-A89352139_2-(5-Phenyl-2H-[1,2,4]triazol-3-yl)-3a,4,7,7a-tetrahydro-isoindole-1,3-dione_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-A89352139_2-(5-Phenyl-2H-[1,2,4]triazol-3-yl)-3a,4,7,7a-tetrahydro-isoindole-1,3-dione_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
ARL4A ADP-ribosylation factor-like 4A
CHIC2 cysteine-rich hydrophobic domain 2
CXCL13 chemokine (C-X-C motif) ligand 13
IFI6 interferon, alpha-inducible protein 6
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
MID1 midline 1
PTN pleiotrophin
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SESN1 sestrin 1
SFRP4 secreted frizzled-related protein 4
SULF1 sulfatase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TTC39A tetratricopeptide repeat domain 39A
TXNIP thioredoxin interacting protein
VCAM1 vascular cell adhesion molecule 1
WFDC1 WAP four-disulfide core domain 1

decreased expression

Symbol Name
ADM adrenomedullin
APLP2 amyloid beta (A4) precursor-like protein 2
AQP3 aquaporin 3 (Gill blood group)
CAB39 calcium binding protein 39
CTSH cathepsin H
CXCL8 chemokine (C-X-C motif) ligand 8
EXOSC4 exosome component 4
FLNA filamin A, alpha
GANAB glucosidase, alpha; neutral AB
GPRC5A G protein-coupled receptor, class C, group 5, member A
HACD2 3-hydroxyacyl-CoA dehydratase 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KIF20A kinesin family member 20A
LMO2 LIM domain only 2 (rhombotin-like 1)
NDN necdin, melanoma antigen (MAGE) family member
NRN1 neuritin 1
OAT ornithine aminotransferase
PSPH phosphoserine phosphatase
RAB4A RAB4A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RCC1 regulator of chromosome condensation 1
RNASE4 ribonuclease, RNase A family, 4
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP1 secreted frizzled-related protein 1
TMED9 transmembrane emp24 protein transport domain containing 9
TSPAN8 tetraspanin 8
YME1L1 YME1-like 1 ATPase