BRD-A89067742_HTS 10765_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-A89067742_HTS 10765_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
CD24 CD24 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COMP cartilage oligomeric matrix protein
EZR ezrin
HBB hemoglobin, beta
LGALS4 lectin, galactoside-binding, soluble, 4
MEF2C myocyte enhancer factor 2C
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
OASL 2'-5'-oligoadenylate synthetase-like
PHGDH phosphoglycerate dehydrogenase
S100A4 S100 calcium binding protein A4
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYBU syntabulin (syntaxin-interacting)
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
CENPU centromere protein U
CIRBP cold inducible RNA binding protein
COL6A2 collagen, type VI, alpha 2
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
DMXL2 Dmx-like 2
FGF13 fibroblast growth factor 13
FLRT3 fibronectin leucine rich transmembrane protein 3
FN1 fibronectin 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
HN1 hematological and neurological expressed 1
IGFBP3 insulin-like growth factor binding protein 3
KIF14 kinesin family member 14
LOXL2 lysyl oxidase-like 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MSMB microseminoprotein, beta-
NUSAP1 nucleolar and spindle associated protein 1
PCCB propionyl CoA carboxylase, beta polypeptide
PGD phosphogluconate dehydrogenase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A8 S100 calcium binding protein A8
STC1 stanniocalcin 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TSPAN4 tetraspanin 4
TUSC3 tumor suppressor candidate 3
WNT5A wingless-type MMTV integration site family, member 5A