BRD-A79768653_sirolimus_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

79 genes differentially expressed following the BRD-A79768653_sirolimus_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRG2 adhesion G protein-coupled receptor G2
AGTR1 angiotensin II receptor, type 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANXA4 annexin A4
BEX1 brain expressed, X-linked 1
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCNG2 cyclin G2
CD24 CD24 molecule
CD9 CD9 molecule
CLU clusterin
CX3CR1 chemokine (C-X3-C motif) receptor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FCGBP Fc fragment of IgG binding protein
GALC galactosylceramidase
GSTA1 glutathione S-transferase alpha 1
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
ISG15 ISG15 ubiquitin-like modifier
KRT23 keratin 23, type I
MTSS1 metastasis suppressor 1
NNMT nicotinamide N-methyltransferase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PENK proenkephalin
PLSCR3 phospholipid scramblase 3
PODXL podocalyxin-like
RPL38 ribosomal protein L38
SAT1 spermidine/spermine N1-acetyltransferase 1
SOX4 SRY (sex determining region Y)-box 4
STOM stomatin
TIMP1 TIMP metallopeptidase inhibitor 1
TM4SF4 transmembrane 4 L six family member 4
TP53 tumor protein p53
TRAPPC6A trafficking protein particle complex 6A
TST thiosulfate sulfurtransferase (rhodanese)

decreased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
CBS cystathionine-beta-synthase
CSTA cystatin A (stefin A)
CTH cystathionine gamma-lyase
EIF5 eukaryotic translation initiation factor 5
EIF5A eukaryotic translation initiation factor 5A
FOS FBJ murine osteosarcoma viral oncogene homolog
GARS glycyl-tRNA synthetase
H1F0 H1 histone family, member 0
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
LUM lumican
MAGEA3 melanoma antigen family A3
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP3 matrix metallopeptidase 3
NDC1 NDC1 transmembrane nucleoporin
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDHX pyruvate dehydrogenase complex, component X
PHGDH phosphoglycerate dehydrogenase
PITX1 paired-like homeodomain 1
PPIF peptidylprolyl isomerase F
PRDX2 peroxiredoxin 2
PSAT1 phosphoserine aminotransferase 1
SELL selectin L
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STXBP6 syntaxin binding protein 6 (amisyn)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TIAM1 T-cell lymphoma invasion and metastasis 1
TNC tenascin C
TRPS1 trichorhinophalangeal syndrome I
WARS tryptophanyl-tRNA synthetase
XIST X inactive specific transcript (non-protein coding)