BRD-A76490030_2-[(chloroacetyl)(3,4-dimethylphenyl)amino]-N-cyclohexyl-2-pyridin-3-ylacetamide_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-A76490030_2-[(chloroacetyl)(3,4-dimethylphenyl)amino]-N-cyclohexyl-2-pyridin-3-ylacetamide_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACAN aggrecan
ADD3 adducin 3 (gamma)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ATF3 activating transcription factor 3
CEMIP cell migration inducing protein, hyaluronan binding
COL11A1 collagen, type XI, alpha 1
COL6A1 collagen, type VI, alpha 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FOSL1 FOS-like antigen 1
GAS6 growth arrest-specific 6
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JUN jun proto-oncogene
LCN2 lipocalin 2
NPTX2 neuronal pentraxin II
OLFM4 olfactomedin 4
PPP1R15A protein phosphatase 1, regulatory subunit 15A

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
AMIGO2 adhesion molecule with Ig-like domain 2
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
BTBD3 BTB (POZ) domain containing 3
CD36 CD36 molecule (thrombospondin receptor)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLIC3 chloride intracellular channel 3
DMXL2 Dmx-like 2
GRIA2 glutamate receptor, ionotropic, AMPA 2
HES1 hes family bHLH transcription factor 1
IRS2 insulin receptor substrate 2
LTF lactotransferrin
MAGED1 melanoma antigen family D1
MARCKS myristoylated alanine-rich protein kinase C substrate
MLEC malectin
MLPH melanophilin
PRKCD protein kinase C, delta
PTGER3 prostaglandin E receptor 3 (subtype EP3)
SCGB2A2 secretoglobin, family 2A, member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOX4 SRY (sex determining region Y)-box 4
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TSPAN13 tetraspanin 13