BRD-A75919782_Folinic acid calcium salt_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-A75919782_Folinic acid calcium salt_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATG3 autophagy related 3
CALB2 calbindin 2
CLC Charcot-Leyden crystal galectin
CLDND1 claudin domain containing 1
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
DEPTOR DEP domain containing MTOR-interacting protein
ETV1 ets variant 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
IFI16 interferon, gamma-inducible protein 16
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
LUM lumican
MECOM MDS1 and EVI1 complex locus
MNDA myeloid cell nuclear differentiation antigen
NEB nebulin
NID2 nidogen 2 (osteonidogen)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
POSTN periostin, osteoblast specific factor
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PXDN peroxidasin
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
S100A11 S100 calcium binding protein A11
S100A12 S100 calcium binding protein A12
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TIMP2 TIMP metallopeptidase inhibitor 2
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
VCAN versican
VLDLR very low density lipoprotein receptor
ZEB1 zinc finger E-box binding homeobox 1

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AHCY adenosylhomocysteinase
AQP3 aquaporin 3 (Gill blood group)
CCL20 chemokine (C-C motif) ligand 20
CFB complement factor B
CHN1 chimerin 1
CLU clusterin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCXR dicarbonyl/L-xylulose reductase
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
ETFB electron-transfer-flavoprotein, beta polypeptide
FCGBP Fc fragment of IgG binding protein
FGG fibrinogen gamma chain
GNAS GNAS complex locus
GPM6B glycoprotein M6B
H1F0 H1 histone family, member 0
MT1E metallothionein 1E
NDRG3 NDRG family member 3
NPDC1 neural proliferation, differentiation and control, 1
OLFM1 olfactomedin 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PRDX2 peroxiredoxin 2
PRDX4 peroxiredoxin 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB13 RAB13, member RAS oncogene family
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
RPN2 ribophorin II
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLPI secretory leukocyte peptidase inhibitor
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TGFBI transforming growth factor, beta-induced, 68kDa
TSC22D1 TSC22 domain family, member 1